ZHEJIANG ZANCHENG LIFE SCIENCES LIMITED

浙江赞诚生物科技有限公司

ZHEJIANG ZANCHENG LIFE SCIENCES LIMITED

Specializing in the production and management of intermediates and fine chemicals

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Tert-Butyl bromoacetate

Chemintel Technology

Tert-Butyl bromoacetate

Information
Product name Tert-Butyl bromoacetate
English synonyms T-BUTYLBROMOACETATE;1,1-Dimethylethyl2-bromoacetate;1,1-Dimethylethylbromoacetate;bromoaceticacidT-butylester;Chemicalbooktertiarybutylbromoacetate;2-Bromoaceticacid-t-butylester;#ntert.-Butylbromoacetate;tert-Butylbromoacetate,98%
CAS No. 5292-43-3
Molecular formula C6H11BrO2
Molecular weight 195.05
EINECS No. 226-133-6
Structural formula
Physicochemical properties
Melting point 44-47 °C
Boiling point 50 °C10 mm Hg(lit.)
Density 1.338
Vapor pressure 1.62hPa at 25℃
Refractive index n20/D 1.445(lit.)
Flash point 121 °F
Storage 0-6°C
Solubility Soluble in chloroform and ethyl acetate (in small amounts)
Appearance liquid
Color Transparent, colorless to yellow
Use 1. Tert-butyl bromoacetate is used as a pharmaceutical intermediate for the synthesis of amino acids and peptide compounds. 2. Tert-butyl bromoacetate is a common alkylating agent used for the synthesis of collagenase inhibitor (S,S,R)-(-)-actinonin. It was constructed as a substitute for butyl as the research object.
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